Gas & moisture barrier
Butyl rubber is valued for low gas and water-vapor permeability. Actual protection also depends on the seal between the stopper and the container.
BROMOBUTYL RUBBER · OEM / ODM
A better fit starts with the right closure.
Butyl rubber stoppers for pharmaceutical packaging, sample collection and laboratory containers. From an RSIIR reference model to a custom design, we help turn your closure requirements into a manufacturing brief.

01 / RSIIR DIMENSIONS
Browse 91 butyl rubber stopper models, then send the selected reference with your container drawing for a fit review.

A: body width · B: flange width · C: below-flange height · D: flange thickness · E: internal opening.
The section illustrates an internal recess. Some models have this feature; product photographs show the solid exterior style. Confirm the internal profile, dimension units and tolerances on the agreed model drawing.
| Inquiry | ||||||
|---|---|---|---|---|---|---|
| RSIIR14.5-19.7-11 | 14.5 | 19.7 | 11 | 3 | 0 | Get quote ↗ |
| RSIIR2.5-5.5-5.3 | 2.5 | 5.5 | 5.3 | 2 | 0 | Get quote ↗ |
| RSIIR3-4.3-4.5 | 3 | 4.3 | 4.5 | 0.8 | 0 | Get quote ↗ |
| RSIIR3-7-7 | 3 | 7 | 7 | 2.2 | 0 | Get quote ↗ |
| RSIIR3.5-6.5-6 | 3.5 | 6.5 | 6 | 2 | 0 | Get quote ↗ |
| RSIIR3.8-7-10.5 | 3.8 | 7 | 10.5 | 1.5 | 0 | Get quote ↗ |
| RSIIR3.8-7-7 | 3.8 | 7 | 7 | 1.5 | 0 | Get quote ↗ |
| RSIIR4-7.5-6 | 4 | 7.5 | 6 | 2 | 0 | Get quote ↗ |
| RSIIR4.5-7.5-6 | 4.5 | 7.5 | 6 | 2 | 0 | Get quote ↗ |
| RSIIR4.8-6.8-3.6 | 4.8 | 6.8 | 3.6 | 0.9 | 0 | Get quote ↗ |
| RSIIR5-8-7-2 | 5 | 8 | 7 | 1.5 | 2 | Get quote ↗ |
| RSIIR5-8-7-3 | 5 | 8 | 7 | 1.5 | 3 | Get quote ↗ |
| RSIIR5-10-8 | 5 | 10 | 8 | 2.8 | 0 | Get quote ↗ |
| RSIIR5.7-11.7-12 | 5.7 | 11.7 | 12 | 6.5 | 0 | Get quote ↗ |
| RSIIR6-8-5 | 6 | 8 | 5 | 2.2 | 0 | Get quote ↗ |
A–E values follow the RSIIR reference schedule. E = 0 entries are retained as listed. Use the model drawing to confirm the final construction before ordering.
02 / CLOSURE PERFORMANCE
Vial stoppers do more than cover an opening. The compound, geometry and container work together to control contact, sealing and access.
Butyl rubber is valued for low gas and water-vapor permeability. Actual protection also depends on the seal between the stopper and the container.
Rubber vial stoppers deform against the mating surface. Fit and compression must allow the compound to maintain contact during the intended use.
For needle-access applications, pharmaceutical rubber stoppers require an appropriate balance of penetrability, fragmentation and resealing performance.
Choose bromobutyl rubber stoppers around the contents and service conditions. Review contact compatibility using the selected formulation.
Performance is specific to the selected compound, part design and complete closure system. Confirm requirements with application samples.
03 / APPLICATIONS
Explore where pharmaceutical stoppers and laboratory closures are used. Each application calls for its own material and geometry review.

PHARMACEUTICAL PACKAGING
Rubber vial stoppers form the elastomer contact surface between a vial and its closure. For liquid formulations and vaccine vial stoppers, select the compound and fit around the contents, vial neck and intended needle access.
Selection focusReview neck finish, closure compression and formulation contact.
Discuss this application ↗
LYOPHILIZATION
Pharmaceutical vial rubber stoppers for freeze-drying need a geometry that allows vapor to escape during processing and closes fully afterwards. Discuss a dedicated venting design for this application.
Selection focusA standard solid RSIIR profile is not automatically a freeze-drying design.
Discuss this application ↗
LIQUID CONTAINMENT
Butyl stoppers can form the closure or access component of a glass infusion container. The neck, retaining closure and intended piercing device must be evaluated together.
Selection focusDefine insertion force, retention and the intended access device.
Discuss this application ↗
SAMPLE COLLECTION
A collection tube closure helps retain the pressure difference before use and seals around the intended sampling interface. Rubber stopper geometry and the tube assembly jointly affect performance.
Selection focusEvaluate vacuum retention and closure fit in the complete tube.
Discuss this application ↗
LABORATORY APPLICATIONS
Serum vial stoppers and sample-bottle closures help limit exchange with the surrounding air. Match butyl rubber stoppers to the sample medium, sampling method and storage conditions.
Selection focusConfirm compatibility, sample contact and the expected number of accesses.
Discuss this application ↗Application images illustrate closure use. The 91 RSIIR reference models are not interchangeable across all container systems.
04 / MATERIAL & FINISH
Our factory manufactures bromobutyl rubber stoppers to your closure requirements. Tell us about the contents and service conditions so we can review the compound and geometry.
A halogenated butyl compound family used in pharmaceutical vial stoppers and other container closures. Discuss the formulation, hardness and geometry needed for your application.
Bromobutyl and chlorobutyl are both used to make halogenated butyl rubber stoppers. Compare specific formulations rather than assuming identical performance or substituting one compound for another.

Blue butyl rubber stoppers, along with gray, white and black, are examples of the colors we offer. We can also customize the color to your requirements. Send a color reference or physical sample so we can review your target shade and confirm it with a product sample. Color is a design choice, not a performance classification.
05 / USE & HANDLING
Use these checkpoints when selecting vial rubber stoppers, reviewing samples and preparing the assembly process.
Check the neck bore, sealing surface and retaining closure against the agreed drawing. A nominal vial size alone does not establish the correct stopper fit.
Use the intended insertion and closing process. Too little contact can leave a leakage path; excessive deformation can affect seating and recovery.
Assess the exact compound with the formulation or sample medium, including contact time and temperature. Material family names do not replace an application-specific evaluation.
Specify the needle or access device and expected access count. Review penetration, fragments and resealing using the actual closure assembly; repeated access is not an unlimited-use claim.
Check for damage, foreign matter, distortion and dimensional variation. Keep the sealing faces protected during handling and separate parts that do not match the approved sample.
Keep parts in their original protective packaging, away from direct sunlight, heat, ozone sources and unintended chemical contact. Confirm storage conditions for the selected compound.
06 / FROM DRAWING TO SUPPLY
Work directly with a butyl rubber stopper manufacturer on reference models, drawing-based production and application-led development.
OEM butyl stoppers follow your specified geometry and material requirements. Share critical dimensions, color and container details for a manufacturing review.
ODM butyl stoppers begin with the function: what needs to seal, what it contacts and how it will be used. We review material and shape with your team before sample evaluation.
For a production order, send an RSIIR model or drawing and the quantity you need. Our factory will review the compound, color, packaging and repeat-order requirements with your team.
Application, drawing and volume
Compound, dimensions and color
Fit and function in your assembly
Approved specification and order
07 / TECHNICAL & PURCHASING FAQ
Practical answers for teams sourcing pharmaceutical rubber stoppers and custom butyl closures.
Ask our team ↗High performance vial stoppers must meet the needs of a specific container system. Define the barrier, sealing, piercing and contact requirements first, then evaluate the selected compound and geometry against those requirements.
Ask how the proposed compound and part drawing relate to your container, which features need sample evaluation and how your approved specification will be identified on repeat orders. As a pharmaceutical rubber stoppers manufacturer, we start the discussion with your application and drawing.
Yes. STOPPER FACTORY provides butyl rubber stoppers, including bromobutyl rubber stoppers, with OEM and ODM manufacturing. Send a drawing, intended application and order quantity so we can review your project.
We provide bromobutyl rubber stoppers. Bromobutyl and chlorobutyl both belong to the halogenated butyl rubber family, but a chlorobutyl specification should be discussed separately. We do not treat the two compounds as interchangeable.
Yes. Our OEM butyl stoppers can follow your drawing, while ODM butyl stoppers start with an application brief and design review. The blue, gray, white and black stoppers shown are examples. We also offer custom colors to meet your requirements. Share a color reference or physical sample, and confirm the final compound and shade with a product sample.
Compare the RSIIR dimensions with your container drawing, then evaluate samples in the complete assembly. Neither the product photograph nor a nominal 13 mm or 20 mm vial designation is enough to confirm compatibility.
No. The product photographs show a solid external appearance. Some models have an internal opening or recess, represented by the section drawing and the E column. Confirm the exact internal profile, depth and dimensions on the model drawing before ordering.
Selection depends on the exact compound, contents, closure geometry and use conditions. Pharmaceutical stoppers should be assessed as part of the intended container system, including contact compatibility and closure performance.
Contact our team for samples and wholesale butyl stoppers. For wholesale pharmaceutical rubber stoppers, include the intended use, model or drawing, quantity per order and forecast demand so we can prepare a project-specific quotation.
Send the container and stopper drawings, contact medium, preferred material and color, quantity and any critical fit or access requirements. We use these details to review OEM pharmaceutical rubber stoppers and ODM pharmaceutical rubber stoppers with your team.
LET’S REVIEW YOUR APPLICATION
Send a model number or drawing, your application, preferred color and quantity. Our team will review the next steps for your butyl rubber stoppers.